Idiopathic inflammatory myopathies: Current and future therapeutic options
نویسندگان
چکیده
منابع مشابه
Current pharmacological treatment of idiopathic inflammatory myopathies.
The idiopathic inflammatory myopathies are uncommon and heterogeneous disorders. Their classification is based on distinct clinicopathologic features. Although idiopathic inflammatory myopathies share some similarities, different subtypes may have variable responses to therapy, so it is very important to distinguish the correct subtype. There are few randomised, double blind placebo controlled ...
متن کاملResistin in idiopathic inflammatory myopathies
INTRODUCTION The purpose of this study was to evaluate and compare the serum levels and local expression of resistin in patients with idiopathic inflammatory myopathies to controls, and to determine the relationship between resistin levels, inflammation and disease activity. METHODS Serum resistin levels were determined in 42 patients with inflammatory myopathies and 27 healthy controls. The ...
متن کاملAutoantibodies in Idiopathic Inflammatory Myopathies
Autoimmune response to nuclear and cytoplasmic autoantigens is detected in about 60-80% of patients affected with idiopathic inflammatory myositis such as polymyositis (PM), dermatomyositis (DM) and inclusion body myositis (IBM). Some of the serum autoantibodies are shared with other autoimmune diseases (myositis-associated antibodies MAA) and some of them are unique to myositis (myositis-speci...
متن کاملChemokines in idiopathic inflammatory myopathies.
The idiopathic inflammatory myopathies (IIM) represent a heterogeneous group of acquired muscle diseases. The three best-studied subgroups: dermatomyositis (DM), polymyositis (PM), and sporadic inclusion body myositis (IBM), differ considerably both clinically and pathophysiologically. DM is a chiefly humoral endotheliopathy often associated with characteristic skin manifestations. In PM and IB...
متن کاملClassification of Idiopathic Inflammatory Myopathies
15 DOI 10/1007/978-1-60327-827-0_2, © Humana Press. a part of Springer Science + Business Media, LLC 2009 Abstract Although it has been long recognized that inflammatory muscle disease of unknown etiology may present clinically and respond to therapy in a variety of ways, our approaches regarding how to best classify or divide these entities into more understandable groups of patients has evolv...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neurotherapeutics
سال: 2008
ISSN: 1933-7213,1878-7479
DOI: 10.1016/j.nurt.2008.08.008